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Send Us Email contact@americanregen.com
Call Us Now (248) 876-4242
Ozone injection therapy is a targeted form of regenerative ozone treatment in which a precise, medically-graded mixture of ozone (O3) and oxygen is administered directly into a specific area of the body — such as a painful joint, inflamed bursa, trigger point, or damaged soft tissue — using a fine needle.
Unlike systemic ozone therapy, which works throughout the bloodstream, ozone injections deliver therapeutic reactive oxygen species locally — precisely where pathology exists. This triggers an immediate oxidative healing response: activating local stem cells, increasing collagen production, eliminating pathogens, and reducing inflammation at the source.
At American Regenerative Clinic, ozone injection therapy is always physician-supervised by Dr. Andrey Lutskovsky, and can be combined with PRP, stem cell therapy, or the advanced Hemealumen light-therapy protocol for even greater regenerative effect.
Medical-grade oxygen is passed through a certified ozone generator to create a precise O3/O2 mixture at a physician-determined therapeutic concentration.
Using a fine needle — and imaging guidance when appropriate — the ozone mixture is placed precisely into the affected joint, muscle layer, bursa, or soft tissue.
Ozone reacts with local tissue to release reactive oxygen species, stimulating mitochondrial function, activating dormant stem cells, and modulating inflammatory cytokines.
The body’s natural repair cascade accelerates — collagen synthesis increases, cartilage is supported, blood flow improves, and pain signals diminish as tissue heals.
Ozone injected directly into painful joints or muscles neutralizes inflammatory mediators and promotes tissue repair at the precise source of discomfort — without the systemic side effects of corticosteroids.
The controlled oxidative burst from ozone activates fibroblasts and local stem cells, accelerating collagen synthesis, cartilage repair, and cellular regeneration in damaged areas.
Ozone is lethal to bacteria, viruses, fungi, and spirochetes on contact. Injected into compromised tissue, it eliminates pathogens directly — without antibiotics or systemic drug exposure.
Ozone enhances microcirculation at the injection site — improving oxygen delivery to oxygen-starved tissues, reducing ischemia, and restoring function to affected areas.
By modulating inflammatory pathways and reducing prostaglandin production, ozone reduces chronic swelling — often replacing the need for repeated cortisone injections.
Patients report significant improvements in range of motion, joint flexibility, and daily functional capacity — allowing return to activities that pain had previously made impossible.
Schedule your consultation. Our team will evaluate your condition and design a personalized EBOO treatment protocol for you.
Have a light meal before your appointment. Avoid coming in fasted — blood sugar stability supports a comfortable procedure and better overall outcomes.
Hydrate well the day before and the morning of your injection. Proper hydration improves tissue perfusion and supports efficient ozone uptake at the injection site.
Inform Dr. Lutskovsky of all current medications, supplements, and any known drug allergies before the procedure to ensure your protocol is safe and fully optimized.
Ozone injection therapy will not impair your ability to drive, work, or complete regular daily tasks. You may resume your full normal routine immediately after the session.
If you have experienced difficulty with past injections or blood draws, please let our team know in advance so we can take additional measures to ensure your comfort.
We encourage patients to explore reputable ozone therapy references before their visit, including aaot.us and oxygenhealingtherapies.com.