What is Extracorporeal Blood Oxygenation and Ozonation (EBOO)?

You may have heard the term EBOO as it becomes more well-known in the world of advanced ozone therapy, which has been used for generations. Extracorporeal Blood Oxygenation and Ozonation, or EBOO, is mainly used in treating toxicity and chronic illnesses. But what exactly is EBOO and could it be right for you? Let’s find out!

Ozone - EBOO therapyHow Does EBOO work?

EBOO is actually a form of dialysis. It uses a dialysis filter to clean blood from the debris of destroyed germs, heavy metals, fungus, and more, and to ozonate the blood in stages. Essentially, as blood is drawn from a vein, it goes through the filter where it is ozonated, and then is reintroduced to the body through a different vein. The entire process only takes about 45 minutes! Because it is a closed system, where the blood is never exposed to outside elements, it eliminates the possibility of contamination. The course takes 3 procedures, 1 week apart, which normally repeats twice a year.

Who Can EBOO Treatments Help?

EBOO is known to have beneficial effects in killing viruses, eliminating bacteria, and neutralizing toxic substances. Ozone therapy in general, of which EBOO is the most advanced form, can be helpful for a number of disorders including joint pain in the knees, lower back, hip, shoulder, elbows, and neck, inflammatory conditions such as arthritis, bursitis, nephritis, cholecystitis, pancreatitis, proctitis, and cystitis.

One of EBOO’s strongest effects is pain management, which these disorders are known for and can be the most debilitating factor in dealing with them. It can also be helpful in autoimmune disorders like fibromyalgia, rheumatoid arthritis, and multiple sclerosis, again known for their painful effects on the body.

In a study published in 2005, patients with peripheral artery disease (PAD) were given EBOO treatments in a clinical trial to determine whether their skin lesions improved. The patients who were treated with EBOO showed significant regression of skin lesions as compared to the other form of treatment given to the other set of patients (prostacyclin).1 Not only did the skin lesions regress but the patients who received the EBOO treatments also reported less pain and better overall well-being.

Ozone therapies can also be useful for patients with viral infections, bacterial infections, cardiovascular diseases, eye diseases, skin disorders, respiratory diseases, heavy metal poisoning, and other conditions like fungal/yeast infections, tetanus, and chronic fatigue. Learn more examples of the types of conditions EBOO and ozone therapies can assist with here.

How Can American Regenerative Clinic Help You?

At American Regenerative Clinic we care about our patients and strive to administer only the highest possible quality of care. If you are wondering if Ozone Therapy or EBOO is the right option for yourself or someone you know, schedule an appointment with Dr Lutskovsky. 

Call us at American Regenerative Clinic if you have questions about these or any other treatments, and find the one that’s right for you.


  1. Di Paolo N, Bocci V, Salvo DP, et al. Extracorporeal Blood Oxygenation and Ozonation (EBOO): A Controlled Trial in Patients with Peripheral Artery Disease. The International Journal of Artificial Organs. 2005;28(10):1039-1050. 

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